Publications
Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP-dependent Regulation. Ong, W., N. Marinval, J. Lin, M.H. Nai, Y.-S. Chong, C. Pinese, S. Sajikumar, C.T. Lim, C. ffrench-Constant, M.E. Bechler, and S.Y. Chew. 2020. Small. 16(37): 2003656.
doi:10.1002/smll.202003656
Oriented and Sustained Protein Expression on Biomimicking Electrospun Fibers for Evaluating Functionality of Cells. Lin, J., W. H. Chooi, W. Ong, N. Zhang, M.E. Bechler, C. ffrench-Constant, and S.Y. Chew. 2020. Mater Sci Eng C. 116: 111407.
doi:10.1016/j.msec.2020.111407
A Neuron-free Microfiber Assay to Assess Myelin Sheath Formation.
M.E. Bechler. 2019. Methods in Molecular Biology. Oligodendrocytes: Methods and Protocols. Eds. D. Lyons and L. Kegel, Springer. 1936: 97-110.
doi: 10.1007/978-1-4939-9072-6_6
Scaffold-Mediated Sustained, Non-Viral Delivery of miR-219/miR-338 Promotes CNS Remyelination.
Milbreta, U*., J. Lin*, C. Pinese, W. Ong, J.S. Chin, H. Shirahama, R. Mi, A. Williams, M.E. Bechler, J. Wang, C. ffrench-Constant, A. Hoke, and S.Y. Chew. 2019. Mol Ther. 27(2):411-423.
doi:10.1016/j.ymthe.2018.11.016
Microfiber Drug/Gene Delivery Platform for Study of Myelination.
Ong, W., J. Lin, M.E. Bechler, K. Wang, M. Wang, C. ffrench-Constant, and S.Y. Chew. 2018. Acta Biomaterialia. 75:152-160.
doi:10.1016/j.actbio.2018.06.011
Activin Receptors Regulate the Oligodendrocyte Lineage in Health and Disease.
Dillenburg, A., G. Ireland, R.K. Holloway, C.L. Davies, F.L. Evans, M. Swire, M.E. Bechler, D. Soong, T.J. Yuen, G.H. Su, J.C. Becher, C. Smith, A. Williams, and V.E. Miron. 2018. Acta Nuropathol. 135(6):887-906.
doi:10.1007/s00401-018-1813-3
Intrinsic and Adaptive Myelination – a Sequential Mechanism for Smart Wiring in the Brain.
Bechler, M.E., M. Swire, and C. ffrench-Constant. 2018. Dev Neurobiol. 78(2): 68-79
doi:10.1002/dneu.22518
Reconstitution of Phospholipase A2-Dependent Golgi Membrane Tubules.
Cluett, E.B., P. de Figueiredo, M.E. Bechler, K.D. Thorsen, and W.J. Brown. 2016. Methods in Molecular Biology. The Golgi Complex: Methods and Protocols. Ed. W. Brown, Springer. 1496: 75-90.
doi:10.1007/978-1-4939-6463-5_7
CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes.
Bechler, M.E., L. Byrne, and C. ffrench-Constant. 2015. Curr Biol. 25(18): 2411-2416.
doi:10.1016/j.cub.2015.07.056
A New Wrap for Neuronal Activity?
Bechler, M.E. and C. ffrench-Constant. 2014. Science. 344(6183): 480-481.
doi:10.1126/science.1254446
Gβ1γ2 Activates Phospholipase A2-Dependent Golgi Membrane Tubule Formation.
Bechler, M.E. and W.J. Brown. 2014. Front Cell Dev Biol. 2(4).
doi:10.3389/fcell.2014.00004
PAFAH Ib Phospholipase A2 Subunits Have Distinct Roles in Maintaining Golgi Structure and Function.
Bechler, M.E. and W.J. Brown. 2013. Biochim Biophys Acta. 1831: 595-601.
doi:10.1016/j.bbalip.2012.12.004
A PLA1-2 Punch Regulates the Golgi Complex.
Bechler, M.E., P. de Figueiredo and W.J. Brown. 2011. Trends Cell Biol. 22: 1–9.
doi:10.1016/j.tcb.2011.10.003
The Phospholipase A2 Enzyme Complex PAFAH Ib Mediates Endosomal Membrane Tubule Formation and Trafficking.
Bechler, M.E., A.M. Doody, K.D. Ha, B.L. Judson, I. Chen, and W.J. Brown. 2011. Mol Biol Cell. 22: 2348–2359.
doi:10.1091/mbc.E09-12-1064
The Phospholipase Complex PAFAH Ib Regulates the Functional Organization of the Golgi Complex.
Bechler, M.E.*, A.M. Doody*, E. Racoosin, L. Lin, K. Lee and W.J. Brown. 2010. J Cell Biol. 190: 45-53.
doi:10.1083/jcb.200908105