Marie Bechler, PI
Dr. Marie Bechler joined the Dept. of Cell and Developmental Biology at SUNY Upstate Medical University as an Assistant Professor in Dec. 2019.
Marie received her B.S. in Biochemistry in 2003 from The University of Wisconsin - Madison. As a graduate student she worked with Dr. William J. Brown, focusing on fundamental questions of cellular organization by examining mechanisms of intracellular trafficking. She earned her Ph.D. in Biochemistry, Molecular and Cell Biology from Cornell University in 2011. Her interest in cellular shape and organization continued in her postdoc with Dr. Charles ffrench-Constant at the MRC Centre for Regenerative Medicine, University of Edinburgh.
During her postdoc, Marie made the surprising discovery that oligodendrocytes only require physical cues to create myelin sheaths with equivalent architecture to myelin sheaths in vivo, challenging the predominant view that myelin sheath formation is solely initiated by biochemical cues. This established a role for oligodendrocytes in self-control of myelin sheath formation. The goal of her lab is to define the mechanosensitive and developmentally programmed signals that allow oligodendrocytes generate myelin sheaths reflecting their in vivo origin. The overarching aim is to gain insight into nervous system function and inform strategies to treat neurodevelopmental disorders and neurodegenerative diseases.
Out of the lab, Marie loves hiking & enjoying the outdoors, cooking, traveling, seeking out new food & drinks, and spending time with her partner & two little girls.
Prior to joining our research team, she completed her BS in Microbiology (Hons) from St. Xavier’s College, Kolkata, India and her MS in Biophysics and Molecular Biology from University of Calcutta,
India. She is interested in studying neurodevelopmental mechanisms and disorders. Here, she is focusing the cues to form myelin sheaths and to promote their elongation in response to axon diameter. Outside lab, you can find her either traveling, painting or cooking!